Rhodium(III)-catalyzed C-H activation/annulation with vinyl esters as an acetylene equivalent.
نویسندگان
چکیده
The behavior of electron-rich alkenes in rhodium-catalyzed C-H activation/annulation reactions is investigated. Vinyl acetate emerges as a convenient acetylene equivalent, facilitating the synthesis of sixteen 3,4-unsubstituted isoquinolones, as well as select heteroaryl-fused pyridones. The complementary regiochemical preferences of enol ethers versus enol esters/enamides is discussed.
منابع مشابه
Rhodium-Catalyzed C-H Annulation of Nitrones with Alkynes: A Regiospecific Route to Unsymmetrical 2,3-Diaryl-Substituted Indoles.
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ورودعنوان ژورنال:
- Organic letters
دوره 16 18 شماره
صفحات -
تاریخ انتشار 2014